{"id":5120,"date":"2022-12-01T20:22:50","date_gmt":"2022-12-01T20:22:50","guid":{"rendered":"https:\/\/senomedical.com\/?p=5120"},"modified":"2025-06-16T20:23:10","modified_gmt":"2025-06-16T20:23:10","slug":"poster-presentation-at-rsna-compares-seno-medicals-oa-us-breast-imaging-with-ai-decision-support-to-ultrasound-alone-finds-significantly-better-specificity-to-support-clinical-decision-makin","status":"publish","type":"post","link":"https:\/\/senomedical.com\/index.php\/2022\/12\/01\/poster-presentation-at-rsna-compares-seno-medicals-oa-us-breast-imaging-with-ai-decision-support-to-ultrasound-alone-finds-significantly-better-specificity-to-support-clinical-decision-makin\/","title":{"rendered":"Poster Presentation at RSNA Compares Seno Medical\u2019s OA\/US Breast Imaging with AI Decision Support to Ultrasound Alone; Finds Significantly Better Specificity to Support Clinical Decision Making Conf"},"content":{"rendered":"<p><i>[SAN ANTONIO, TX \u2013<strong>\u00a0December 1, 2021<\/strong>]\u00a0<\/i>A study presented at the Radiological Society of North America (RSNA)\u2019s annual meeting showed Texas-based Seno Medical Instruments, Inc. (Seno)\u2019s Imagio<sup>\u00ae\u00a0<\/sup>opto-acoustic ultrasound (OA\/US) breast imaging provides significantly better specificity than ultrasound alone. The poster, \u201cPerformance of Optoacoustic Ultrasound with an Artificial Intelligence-based Decision Support Tool vs Ultrasound Alone to Classify Benign Versus Malignant Breast Masses: A Pivotal Reader Study,\u201d was presented by Stephen Seiler, MD, Associate Professor, Breast Imaging Division, Department of Radiology at UT Southwestern (Dallas, TX) on November 30.<\/p>\n<p>The study intended to evaluate the gain in specificity using opto-acoustic ultrasound images and an AI-based decision support tool verses ultrasound alone.\u00a0 The study found that OA\/US, when used with a decision support tool, has statistically significant better specificity compared to conventional ultrasound alone.<\/p>\n<ul>\n<li>Fifteen readers with a wide range of experience in breast imaging from both private practice (8) and academic (7) were involved with the reader study.<\/li>\n<li>Opto-acoustic ultrasound achieved the primary endpoint in this reader study with specificity significantly higher for OA\/US (47.2%) compared to ultrasound alone (38.2%), a difference of 9 percent.<\/li>\n<li>The observed specificity was 50.1 percent for IUS+OA and 36.6 percent for US. At fixed 98 percent sensitivity, there was a 13.5 percent observed specificity advantage.<\/li>\n<li>There were 1510 BI-RADS 4A reads of benign masses based on review of US alone.\u00a0 IUS+OA resulted in the appropriate downgrading of 753 (49.8%) reads to either BI-RADS 2 or BI-RADS 3.<\/li>\n<\/ul>\n<p>\u201cOA imaging provides different, yet complementary, diagnostic information not provided by conventional ultrasound or its submodalities of Doppler and elastography,\u201d concluded Seiler.<\/p>\n<p>\u201cWhen used alongside the AI decision support tool, OA imaging has the potential to reduce false positives and thus biopsies of benign masses, versus ultrasound alone, without sacrificing sensitivity.\u201d<\/p>\n<p>Breast biopsy procedures caused by false-positive diagnostic assessments in the United States cost the healthcare system more than $2 billion per year.<a href=\"https:\/\/senomedical.com\/newsroom\/press-releases\/P18#_edn1\">[i]<\/a>\u00a0Seno\u2019s Imagio<sup>\u00ae\u00a0<\/sup>technology could mitigate that with its non-invasive OA\/US technology to help physicians better differentiate between benign and malignant breast lesions in real time, helping providers characterize and differentiate masses that may\u2014or may not\u2014require more invasive diagnostic evaluation.<\/p>\n<p>Seno\u2019s Chief Executive Officer, Tom Umbel, commented, \u201cThe findings by Dr. Seiler and his collaborators further validate the potential for our Imagio<sup>\u00ae<\/sup>\u00a0Breast Imaging System to improve patient care by reducing unnecessary biopsy procedures and supporting clinical decision making confidence.\u201d<\/p>\n<p>The company\u2019s OA\/US technology combines laser optics and grayscale ultrasound to provide fused functional and anatomical breast imaging. The opto-acoustic images provide a unique blood map in and around breast masses, while the ultrasound provides a traditional anatomical image. Through the appearance or absence of two hallmark indicators of cancer \u2013 angiogenesis and deoxygenation\u00a0\u2013 Seno Medical has shown that the Imagio<sup>\u00ae<\/sup>\u00a0OA\/US Breast Imaging System will be a more effective tool to help radiologists confirm or rule out malignancy compared to traditional diagnostic imaging modalities \u2013 without exposing patients to potentially harmful ionizing radiation (x-rays) or contrast agents. In addition to the novel imaging provided by the Imagio<sup>\u00ae<\/sup>\u00a0System, Seno includes an artificial intelligence (AI) decision-support tool (the SenoGram<sup>\u00ae<\/sup>)<sup>\u00a0<\/sup>to aid physicians in interpreting the new images that, along with training and certification, helps radiologists make the transition from ultrasound alone to OA\/US imaging.<\/p>\n<p>The system is indicated for use by trained and qualified healthcare providers to evaluate palpable and non-palpable breast abnormalities in adult patients who are referred for diagnostic imaging breast work-up following clinical presentation or other imaging examinations such as screening mammography.<\/p>\n<p><s>\u00a0<\/s><\/p>\n<p><strong>Seno Medical Instruments, Inc.\u00a0<\/strong>is a San Antonio, Texas-based medical imaging company committed to the development and commercialization of a new modality in cancer diagnosis: opto-acoustic imaging. Approved by the US FDA in January 2021, Seno Medical\u2019s Imagio<sup>\u00ae<\/sup>\u00a0Breast Imaging System fuses opto-acoustic technology with ultrasound (OA\/US) to generate real-time functional and anatomical images of the breast.\u00a0To learn more about Seno Medical\u2019s OA\/US imaging technology and applications, visit\u00a0<a href=\"http:\/\/www.senomedical.com\/\">www.SenoMedical.com<\/a>.<\/p>\n<p>[i] Vlahiotis A, Griffin B, Stavros AT, Margolis J. Analysis of utilization patterns and associated costs of the breast imaging and diagnostic procedures after screening mammography.\u00a0<i>Clinicoeconomics Outcomes Res<\/i>\u00a02018;10:157-167.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>[SAN ANTONIO, TX \u2013\u00a0December 1, 2021]\u00a0A study presented at the Radiological Society of North America (RSNA)\u2019s annual meeting showed Texas-based Seno Medical Instruments, Inc. (Seno)\u2019s Imagio\u00ae\u00a0opto-acoustic ultrasound (OA\/US) breast imaging provides significantly better specificity than ultrasound alone. The poster, \u201cPerformance of Optoacoustic Ultrasound with an Artificial Intelligence-based Decision Support Tool vs Ultrasound Alone to Classify [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[22],"tags":[],"class_list":["post-5120","post","type-post","status-publish","format-standard","hentry","category-press-releases"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Poster Presentation at RSNA Compares Seno Medical\u2019s OA\/US Breast Imaging with AI Decision Support to Ultrasound Alone; Finds Significantly Better Specificity to Support Clinical Decision Making Conf - Seno Medical<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/senomedical.com\/index.php\/2022\/12\/01\/poster-presentation-at-rsna-compares-seno-medicals-oa-us-breast-imaging-with-ai-decision-support-to-ultrasound-alone-finds-significantly-better-specificity-to-support-clinical-decision-makin\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Poster Presentation at RSNA Compares Seno Medical\u2019s OA\/US Breast Imaging with AI Decision Support to Ultrasound Alone; Finds Significantly Better Specificity to Support Clinical Decision Making Conf - Seno Medical\" \/>\n<meta property=\"og:description\" content=\"[SAN ANTONIO, TX \u2013\u00a0December 1, 2021]\u00a0A study presented at the Radiological Society of North America (RSNA)\u2019s annual meeting showed Texas-based Seno Medical Instruments, Inc. (Seno)\u2019s Imagio\u00ae\u00a0opto-acoustic ultrasound (OA\/US) breast imaging provides significantly better specificity than ultrasound alone. 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